Box jellyfish antidote: Potential way to treat sting of world’s most venomous sea creature

The jellyfish has about 60 tentacles that will can grow up to 3 meters (almost 10 feet). They live mainly in coastal waters around the north along with west of Australia along with the Philippines, according to the university’s press Discharge.

Each tentacle has millions of microscopic hooks filled with venom, along with the jellyfish carries enough venom to kill more than 60 humans, the university said. Associate Professor Greg Neely, one of the study’s authors, said no various other animal carries that will amount of venom.

The venom can cause tissue necrosis, extreme pain, cardiac arrest along with death within minutes after severe exposure. If the idea doesn’t kill, the venom can cause excruciating pain.

“We studied the biggest, most venomous along with scary one,” Neely said in a news Discharge. “Our drug works on the big beast. We don’t know yet if the idea works on various other jellyfish, however we know the idea works on the most-deadly one.”

Researchers found that will the venom does most of its damage to the skin when the idea interacts with cholesterol, along with that will drugs that will already exist to eliminate cholesterol also can work as antidotes for box jellyfish venom if the idea is usually administered within 15 minutes of the sting.

Researchers used specific types of cyclodextrins, a family of drugs that will absorb cholesterol, to block the venom, Neely said.

“the idea turns out by blocking the venom’s ability to kill the cells, we can also block some of the pain,” Neely, an associate professor at the University of Sydney who studies diseases along with pain, told CNN.

The antidote was first tested on human cells outside the body along with on live mice, according to the university. Researchers wish to develop a topical application for humans.

However, the idea’s unclear if the antidote will be effective for severe stings.

“We don’t know yet if the idea will stop a heart attack. that will will need more research along with we are applying for funding to continue that will work,” Neely said.

In a piece he wrote for The Conversation, Neely said researchers are also looking to develop a treatment for cardiac injection.

Neely told CNN he’s particularly excited about the potential for using CRISPR to study various other types of venom.

“that will is usually kind of once (CRISPR) has been used for venom,” he said.

“There’s just an unlimited amount of cool work we could do.”

the idea’s unclear exactly how often people are killed by box jellyfish stings. Experts advise victims to pour vinegar on the wound for at least 30 seconds.
The Australian box jellyfish (Chironex fleckeri) is usually considered the earth’s most venomous marine animal, according to the US National Ocean Service.

The jellyfish don’t just float, they can actively swim, gaining speed of 7.5 kilometres an hour (12 miles an hour) when they are hunting, the university said. They feed in shallow waters, mainly smaller fish along with prawns.

Source : Box jellyfish antidote: Potential way to treat sting of world’s most venomous sea creature