Fish in which survive out of water for years could stop ageing in humans

A fish in which can halt the process of ageing in addition to survive out of water for years could help humans track down the fountain of youth, researchers have claimed.

African turquoise killifish can put themselves into a state of suspended animation as an embryo, a characteristic known as diapause.

The trend will be thought to have emerged in response to seasonal alterations within the environment.

Scientists at Stanford University in addition to the Stowers Institute for Medical Research within the US are at This specific point closer to working out how they do the item.

They believe the item could help humans prevent ageing or even hibernate, which may be necessary on future space expeditions.

Scientists are at This specific point closer to working out how they do the item

A study of their DNA shows in which during diapause, genes which trigger the turnover cells dial down, while those involved in muscle maintenance become more active.

Part of This specific seems to be down to an increase within the production of a protein called CBX7.

The authors wrote within the journal Science: “The killifish lives in transient ponds in which are only present during the rainy season in addition to entirely desiccate during the dry season.

“To survive the long drought in addition to enable perpetuation of the species, African killifish embryos enter diapause.

“Although features of diapause have been described in killifish species the mechanisms by which diapause protects organisms remain unknown.

“The time spent in diapause does not come with observed tradeoffs for future life, in addition to diapause confers protective mechanisms to complex organs against damage caused by the passage of time.”

Killifish embryos can put their growth on hold by several months up to two years, matching or even greatly exceeding their typical adult life span.

If humans could do something similar, an 80-year-old person might instead have a life span by 0 to more than 400 years.

Prof Anne Brunet, co-author of the research by Stanford University, told The Guardian: “One can hypothesise in which turning on a “diapause-like” state – or tapping into the molecular machinery of diapause – in some adult tissues or cells could help preserve them long-term.”

She added: “We think the item’s interesting by a fundamental point of view to understand how the accumulation of the damage due to the passage of time can be stopped or suspended.

“Diapause offers us a way to understand This specific.”

Prof Bruney said a better understanding could help slow down the “ageing clock”.

,, 22 February 2020 | 11:40 am

Source : Fish in which survive out of water for years could stop ageing in humans